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Politics : Canadian Political Free-for-All
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To: h_ who wrote (36598)10/6/2025 3:00:10 PM
From: Alastair McIntosh  Read Replies (2) of 37052
 
Are there any vaccines or other treatments that modify DNA?

ChatGPT said:

Good question — this gets asked a lot, especially since the rise of mRNA vaccines.

Here’s the clear breakdown:

?? Vaccines
  • mRNA vaccines (like Pfizer & Moderna COVID-19)

    • These deliver messenger RNA into your cells, which your ribosomes use to make a viral protein (like the spike protein).

    • The mRNA never enters the cell nucleus (where your DNA is) and is broken down within hours.

    • They do not modify your DNA.

  • DNA vaccines (like some under development for Zika or cancer)

    • These use small circular DNA molecules (plasmids).

    • They do enter the cell nucleus but they are not designed to integrate into your genome.

    • Integration into host DNA is extremely rare and not the mechanism by which they work.

  • Traditional vaccines (like measles, polio, flu)

    • These are made of inactivated viruses, weakened viruses, or protein fragments.

    • They have no mechanism at all to modify DNA.

?? Other Medical Treatments
  • Gene therapy

    • This does intentionally modify DNA.

    • It’s used for rare genetic diseases or certain cancers (like CAR-T cell therapy).

    • It’s tightly regulated, expensive, and not a general vaccine-type intervention.

  • CRISPR-based therapies

    • These can directly edit DNA in cells.

    • Still mostly in clinical trials, except for a few approved cases (like certain forms of sickle cell disease).

?? Bottom Line
  • No currently approved vaccine modifies your DNA.

  • Only specialized gene therapies (not vaccines) are designed to alter DNA.

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