Hi Will, We're in luck... found an article on Judy Lewent's work with R&D models. (The article I originally read might have gone into more detail, but this one gets the point across.)
Fortune, 11-13-1995, pp 160+. MANAGING: SUPER CFOS: THEY CAN'T JUMP..(but...)
A new group of CFOs are pushing the envelope by employing academic models to weigh investments. Call them the super-number crunchers. One of the best is Judy Lewent of Merck. Athletically slim in gray pinstriped suits, Lewent, 46, absorbed option theory as an MBA student at MIT in the early 1970s. Even then, she sensed that such breakthroughs would revolutionize thinking not just on campuses but in boardrooms. "My ambition was to use the theory to help run companies," she says. "For me, financial models are the key tools in a CFO's kit." Lewent surrounds herself not with dealmakers but with quants who scour journals and hobnob with professors.
Lewent first displayed her talent as a CFO in the early 1980s. At that time Merck was questioning if new drugs really made money. Its formula for measuring return on investment couldn't project future earnings more than five years after a product's launch. It showed that new drugs barely earned the cost of capital. As a result, Merck pondered diversifying into fields like medical devices. Lewent convinced management to measure the value of projects in the pipeline using a technique called Monte Carlo analysis. The scientists, who used probability theory in their research, liked the idea. Monte Carlo totally contradicted the old model. It showed that Merck held a fabulously profitable portfolio of drugs in development. The answer, Monte Carlo showed, was more R&D, not less.
Instead of producing a single estimate on a drug's future profits, Monte Carlo assigns the probability of every possible outcome 20 years out. The drug, for example, could fail in clinical trials, prove a moderate success, or become a blockbuster. Monte Carlo gives the odds on all three, and all the outcomes in between. Lewent understood that Monte Carlo is perfectly attuned to the drug industry, where one hit has to pay the development costs of dozens of drugs that die in development. "It's like movies or records," says Lewent. "Everyone remembers the Batman Forevers and forgets the Heaven's Gates."
So to raise the probability of discovering the big hits, you have to invest in a greater number of promising new drugs. Starting in 1985, Lewent prodded Merck to lift its annual research budget from $426 million to $1.2 billion today. The results are pleasing. In the past three years Merck has launched a spate of original products, including Fosamax, the first treatment for osteoporosis. Over that period Merck's stock rose 39% to $59, and analysts estimate that next year's earnings will increase 14%.
Lewent's projections also help flag short-term problems. When Monte Carlo estimates show a product is poised just to break even, she recommends using less expensive packaging or retrofitting an existing plant instead of building a new one. That tinkering can turn a lackluster performer that might have been killed into a profit maker. Says she: "Financial types are often accused of being too shortsighted. In our case, the reality is just the opposite."
************************************** Complete article can be obtained at Electric Library, search criteria: Merck CFO.
Laura |