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Gold/Mining/Energy : Zentek Ltd.
ZEN.V 1.170-3.3%Oct 29 3:59 PM EDT
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To: George69 who wrote (53867)10/25/2025 7:43:15 AM
From: George693 Recommendations

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Here is one patent application found at patentscope: Lots of info in this one and lots more to be found at the patentscope site if anyone has the time to dig for other patents.

6. 20250101437APTAMERS FOR DETECTING VARIANTS OF A TARGET ANALYTE, METHODS OF MAKING AND USES THEREOF
US - 27.03.2025

Int.Class C12N 15/115Appl.No 18728342Applicant McMaster UniversityInventor Yingfu Li
This disclosure relates to a method of identifying or producing an aptamer capable of binding to at least two target analyte variants, the method comprises generating a mixture of systematic evolution of ligands by exponential enrichment (SELEX)-selected aptamers by at least one-round of SELEX with a SELEX-compatible aptamer pool against the at least two target analyte variants in parallel or sequentially, sequencing the mixture of SELEX-selected aptamers that form complexes with each of the at least two target analyte variants by high-throughput sequencing, aligning the mixture of SELEX-selected aptamers that form complexes with each of the at least two target analyte variants by sequence alignment analysis, and identifying or producing the aptamer capable of binding to the at least two target analyte variants. Aptamers thereof and uses of the aptamers thereof are also disclosed.
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