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Dec 18 3:59 PM EST

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From: Candu	12/10/2025 6:27:49 PM
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Is anyone at McMaster University working with Graphene oxide for a delivery system including for cancer treatment ChatGPT said: Thought for 17s Short answer: Yes. McMaster researchers (faculty groups and graduate students) are working with graphene/graphene-oxide (GO/rGO) in a variety of projects — including biosensing, functionalization, pH-responsive behaviour and nanocarriers — and some of that work is explicitly tied to drug-delivery concepts that are applicable to cancer therapy. PubMed+2chemistry.mcmaster.ca+2 Who / where (examples and evidence) Li lab (Biochemistry & Biomedical Sciences) — published an rGO + aptamer biosensor platform (shows McMaster expertise combining reduced-graphene-oxide and biological delivery/recognition systems). This group (Dr. Yingfu Li) works on nucleic-acid/aptamer technologies that intersect with graphene materials. PubMed Kruse Research Group (Chemistry / surface science) — active on graphene derivatives (GO/rGO), defect engineering and pH-responsive behaviour that are relevant for designing GO-based delivery systems (for example, pH-responsive release in tumour microenvironments). chemistry.mcmaster.ca+1 Other McMaster theses / student projects — several graduate theses and student projects at McMaster reference graphene oxide used in sensor and delivery-style nanomaterials (macsphere institutional repository). These indicate ongoing lab/student work that uses GO for biomedical/analytical applications. macsphere.mcmaster.ca+1 Context (why this matters) Graphene oxide and its functionalized derivatives are widely studied as drug/gene carriers because of large surface area, easy functionalization and pH/triggerable chemistries; McMaster groups are publishing on the materials and bio-interface aspects that are the building blocks for GO drug-delivery systems. If your interest is specifically GO nanoparticles used in preclinical cancer therapy (in-vivo delivery + animal efficacy), McMaster papers more often address materials, sensing and in-vitro functionalization; translation to in-vivo cancer delivery is less commonly shown in McMaster’s open literature so far (many GO?cancer delivery demonstrations are in the broader literature). MDPI+1

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