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Gold/Mining/Energy : Zentek Ltd.
ZEN.V 1.0000.0%Dec 24 12:03 PM EST
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From: Grapheneman12/22/2025 7:14:17 PM
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As VP & Franchise Head, his responsibilities would have included:
  • P&L oversight for multi-billion-dollar product lines

(I had to ask what P&L oversite was.)
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Here’s a clear, business-grade explanation you can use in a shareholder deck or discussion.

?? What “P&L Oversight” Means P&L oversight refers to an executive’s responsibility for the Profit and Loss statement of a product, business unit, or franchise.
It is one of the highest levels of commercial accountability inside a company.

When someone has P&L oversight, they are responsible for:

?? 1. Revenue Generation They must ensure the business brings in sales through:

  • Pricing strategy
  • Market access and reimbursement
  • Sales force performance
  • Product positioning
  • Launch execution
?? 2. Cost Management They control the major cost drivers that affect profitability:

  • Marketing spend
  • Sales force size and compensation
  • Distribution and logistics
  • Manufacturing costs (if applicable)
  • Medical education and promotional budgets
?? 3. Profitability They are accountable for:

  • Gross margin
  • Operating margin
  • Net profit contribution
  • Meeting quarterly and annual financial targets
This is why P&L oversight is considered a senior executive responsibility — it directly affects shareholder value.

?? 4. Strategic Decision-Making Executives with P&L oversight make decisions such as:

  • Whether to expand into new markets
  • How to respond to competitors
  • When to invest in new indications or lifecycle extensions
  • How to allocate commercial resources
????? 5. Reporting to the CEO and Board They must regularly report:

  • Sales performance
  • Forecast accuracy
  • Budget adherence
  • Market risks and opportunities
This is a high-visibility role inside any pharma or biotech company.

? Why This Matters for John Snisarenko When he was VP & Franchise Head at Genentech, he had P&L oversight for:

  • Lucentis (ophthalmology)
  • Rituxan (rheumatology)
  • Actemra (rheumatology)
These are multi-billion-dollar biologic franchises.

That means he wasn’t just “involved” in commercialization — he was financially accountable for the performance of some of the most important products in Genentech’s portfolio.

This is a major credential for any executive joining a commercial-stage biotech board.

If you want, I can also create:

  • A one-slide explanation of P&L oversight for shareholders
  • A comparison of P&L responsibility at Genentech vs. Zentek
  • A breakdown of how P&L experience strengthens Zentek’s commercialization strategy
Just tell me what you’d like next.
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