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Biotech / Medical : Ligand (LGND) Breakout!
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To: dwc who wrote (16203)3/2/1998 10:39:00 AM
From: Henry Niman  Read Replies (1) of 32384
 
Here's an abstract from a recent review on Cancer Vaccines:

J Am Pharm Assoc (Wash) 1997 Nov;NS37(6):706-709

Cancer vaccines. Part 2.

Hallin PA, Adams VR

M.D. Anderson Cancer Center, Houston, Tex., USA.

Cancer vaccines are being widely studied for the purpose of immune modulation and subsequent
antitumor effects. This article cites only a few examples of the many studies underway. Many
vaccines have shown efficacy in eliciting systemic responses with minimal toxicities. The use of
vaccines as a modality of cancer therapy in combination with chemotherapy, surgery, and radiation
therapy is also being investigated. Although the routine use of approved vaccines is still a goal for the
future, instituting this fourth modality of cancer therapy is not too distant. Phase III trials with both
melanoma and colon cancer vaccines have been completed. Synthetic carbohydrate antigen
vaccines have shown efficacy in several tumor types during Phase II trials and are also generating
enthusiasm. The potential impact of vaccine therapy on the profession of pharmacy may involve
patient counseling regarding management of side effects and possibly also dispensing of vaccine
therapy products to patients directly for home administration. As ambulatory sites open in
conjunction with pharmacy services and pharmacists obtain prescribing authority, pharmacists' active
involvement in vaccine counseling and administration seems likely.

PMID: 9425801, UI: 98086993
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