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Biotech / Medical : IPIC
IPIC 0.00010000.0%Nov 28 9:30 AM EST
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To: Vendit™ who wrote (1076)3/5/1998 6:37:00 AM
From: jlib  Read Replies (1) of 1359
 
>"phen/fen is a mixture of 2 separate prescription drugs. Redux is one of those drugs... AHP is the company that is making this cocktail and sending it to market for resale."<

Just a bit of clarification on the part of your post above. Redux (dexfenfluramine) was rarely prescribed with phentermine. In fact, AHP explicitly advised against it (according to my pharmacist). The fenfluramine part of the phen/fen combination was Pondimin (in the US) and was not connected with IPIC in any way but was solely an AHP product. Redux was similar to Pondimin in effect and composition. In fact, it could be said that dexfenfluramine was the isolated "active ingredient" in fenfluramine. The phentermine portion was an old line anorectic that had long fallen generic so had numerous sources. The phen/fen combo was not a compounded "cocktail" as such but was simply two separate prescriptions. AHP never actively marketed the unapproved combination to physicians (but neither did they actively discourage it). The phen/fen combo off-label usage derived directly from a four year double blind study published in the early 90's by Dr. Michael Weintraub. Several years elapsed before the efficacy of the combination as revealed in the study was accepted by physicians in general. That hesitation pendulumed to the indiscriminate use witnessed before the withdrawal of Pondimin and Redux.

Best,
Jimmy Liberato
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