BJ, I'm still looking (been having problems with SI all day), but I did run across another upcoming conference that will have lots of info on IRs:
Conference Summary and Program
Home Page | Registration Form | Site Descriptions
Nuclear Receptor Gene Family
Incline Village, Nevada ú March 28 - April 3, 1998
Organizers: Kathryn B. Horwitz, John A. Cidlowski and Ron Evans
Maximum Attendance: 450 ú Abstract Deadline: 1/13/98 ú Early Registration: 1/28/98
The steroid, thyroid, retinoic acid and vitamin D receptors, plus a growing number of orphan receptors, are members of a
superfamily of nuclear proteins that regulate transcription. These receptors control, among other things, developmental
processes, tissue-specific differentiation, the growth and death of normal and malignant calls, reproductive behavior and
metabolic activity. They act directly by binding to the hormone response elements of target promoters, or indirectly, by
mechanisms that include interactions with transcriptional corregulators, or cross -talk with other signaling pathways. Among the
problems facing this field are the mechanisms of tissue-specific regulation; cell-cycling and cancer; interactions with
coregulatory factors, transcriptional integration of cell surface/nuclear receptor signals; the regulatory role of chromatin;
post-translational modification of receptors and isoform-specific actions; mechanisms of antagonists; receptor and domain
structure; the function of orphan receptors. The intent of this meeting is to bring together leading experts in this diverse field,
joined by younger investigators and trainees entering the field. The program will include state-of-the art plenary and symposium
lectures plus poster sessions; slots have been set aside for late-breaking developments. Selected student and post-doc
abstracts will be chosen for short oral presentations. Our goal is to nurture and extend the intellectual interaction fostered by
previous Keystone Symposia meetings on this topic.
POSTER TOPICS
Organizer will be assigning poster sessions (no number necessary on form)
Development / Alternate Models / Chromatin / DNA / Transcription / CP Activators / Corepressors / Signaling / Cross-Talk / Orphan Ligands /
Hormone-Induced Repression / Antagonists / Retinoids / Thyroid / Orphans / Non-Traditional Targets / Steroid Receptors
Saturday, March 28
Registration (2-7pm)
Orientation (7-7:30pm)
Keynote Address (7:30-8:30pm)
ROBERT T. TJIAN, Univ California-Berkeley
Enhancers, Core Promoters and Co-Activators: Partners in Directing Transcriptional Regulation
Sunday, March 29
Breakfast (7-8am)
DEVELOPMENT/ALTERNATE MODELS
(8-11am)
CARL THUMMEL, _ Univ of Utah
Nuclear Receptor Function During Drosophila Metamorphosis
SPEAKER TO BE ANNOUNCED
COFFEE BREAK
JOANNE CHORY, Salk Institute
Light, Brassinosteroids, and Plant Development
THOMAS PERLMANN, Ludwig Institute for Cancer Research
Functional Analysis of the Orphan Nuclear Receptors Nurr1, Nor1 and NGFI-B, and of Retinoid Receptor Signaling In vivo
Poster Set-Up (11am-4pm)
Workshop/Poster Abstract Short Talks (3-4pm) (3-4pm)
Poster Session (4-6pm)
Social Hour (5-6pm)
CHROMATIN/DNA (Coffee Available)
(8-10pm)
JAMES KADONAGA, _ Univ California-San Diego
Role of Chromatin Structure in the Regulation of Transcription by the Estrogen Receptorand p300
TREVOR K. ARCHER, Cancer Research Laboratories
Transcriptional Activation Within the Chromatin by the Glucocorticoid Receptors
ALAN WOLFFE, National Institutes of Health
Three Steps in the Regulation of Transcription by the Thyroid Hormone Receptor: Establishment of a Repressive Chromatin Structure,
Distribution of Chromatin and Transcriptional Activation
Monday, March 30
Breakfast (7-8am)
TRANSCRIPTION/COACTIVATORS/COREPRESSORS (8-11am)
ROBERT ROEDER, _ Rockefeller University
The Role of General and Receptor-Associated Coactivators in Thyroid Receptor Function
PETER KUSHNER, Univ California-San Francisco
Recruitment and Triggering of Co-activators By the Estrogen Receptor
COFFEE BREAK
M. GEOFFREY ROSENFELD, Univ California-San Diego
Positive and Negative Transcriptional Regulation in Development
DAVID D. MOORE, Baylor College of Medicine
Coactivators/Corepressors
Workshop/Poster Abstract Short Talks (3-4pm) (3-4pm)
Poster Session (4-6pm)
Social Hour (5-6pm)
SIGNALING/CROSS-TALK (Coffee Available) (8-10pm)
BERT W. O'MALLEY, _ Baylor College of Medicine
Steroid Receptor Coregulators 1998: The Plot Thickens
KATHRYN HORWITZ, Univ of Colorado
Breast Cancer Growth Regulation by Progesterone and Cross-Talk with Epidermal Growth Factor
KENNETH KORACH, National Institutes of Health
Cross coupling of EGF and Estrogen Receptor Signaling Pathways
Tuesday, March 31
Breakfast (7-8am)
ORPHAN LIGANDS (8-11am)
RONALD M. EVANS, _ Salk Institute
Orphan Receptors and Orphan Ligands
DAVID RUSSELL, Univ of Texas SW Medical Center
Androgen Action in Males and Females
RICHARD HEYMAN, Ligand Pharmaceuticals
RXR Agonists Activate RXR:PPAR Gama Heterodimers and Sensitize Diabetic and Obese Mice to Insulin
COFFEE BREAK
STEVEN A. KLIEWER, Glaxo Wellcome
Identification of a Novel Steroid Receptors
CARY WEINBERGER, National Institute Environmental Health Science
Farnesoids, FXR, and Cellular Growth Control
Poster Set-Up (11am-4pm)
Workshop/Poster Abstract Short Talks (3-4pm) (3-4pm)
Poster Session (4-6pm)
Social Hour (5-6pm)
HORMONE-INDUCED REPRESSION/ANTAGONISTS (Coffee Available) (8-10pm)
JOHN A. CIDLOWSKI, National Institute Environment Health Science
GR/NFkB
DONALD MC DONNELL, Duke University
Mechanism Based Approaches for the Discovery of Tissue Selective Agonists and Antagonists for the Estrogen and Progesterone Receptors
SPEAKERS TO BE ANNOUNCED
Wednesday, April 1
Breakfast (7-8am)
RETINOIDS/THYROID/ORPHANS (8-11am)
PIERRE H. CHAMBON, _ Institut de Genetique et de Biologie Moleculaire etCellulaire
Molecular Genetics of Retinoid Receptors
MITCHELL LAZAR, Univ of Pennsylvania
Regulation of Repression by Nuclear Normone Receptors
COFFEE BREAK
ROLAND SCHUELE, University of Freiburg
The Nuclear Orphan Receptors RZRb and GCNF: Structure, Function and Liaison With Novel Cofactors
DAVID MANGELSDORF, Univ of Texas SW Medical Centerr
LXR: The Foie Gras of Nuclear Receptors
Poster Set-Up (11am-4pm)
Workshop/Poster Abstract Short Talks (3-4pm) (3-4pm)
Poster Session (4-6pm)
Social Hour (5-6pm)
NON-TRADITIONAL TARGETS
(Coffee Available) (8-10pm)
DIDIER PICARD, Univ of Geneva
Steroid-Independent Activation of Estrogen and Progesterone Receptors
LEONARD FREEDMAN, Sloan-Kettering Cancer Center
Transcriptional Targets of the Vitamin D3 Receptor Mediating Cell Cycle Arrest and Differentiation
ARUN ROY, Univ of Texas Health Science Center
AR Promoter Function During Aging
Thursday, April 2
Breakfast (7-8am)
STEROID RECEPTORS/CHROMATIN
(8-11am)
CARLOS BUSTAMANTE, _ University of Oregon
Imaging Protein/DNA Interaction with the Scanning Force Microscope
JAN-AKE GUSTAFSSON, Huddinge Hospital
Estrogen Receptor B Predicted Effects of Estrogen
COFFEE BREAK
BENITA S. KATZENELLENBOGEN, University of Illinois
New Dimensions in Estrogen Receptor Pharmacology
DEAN P. EDWARDS, Univ of Colorado Health Science Center
The Role of Chromatin HMG Proteins in Steroid Receptor Action"
NEW DEVELOPMENTS/SHORT TALKS
(2-5pm)
BRUCE M. SPIEGELMAN, Dana Farber Cancer Institute
Transcriptional regulation of Energy Balance By PPARy and Novel Coactivators
ANTHONY WRIGHT, Karolinska Institute
Structure and Function of the Glucocorticoid Receptor N-Terminal Transactivation Domain
COFFEE BREAK,
GUNTHER SCHUTZ, German Cancer Research Center
Analysis of Glucocorticoid Signaling by Gene Targeting
SPEAKER TO BE ANNOUNCED
Social Hour (7-8pm)
Banquet (8-10pm)
Entertainment (9pm-12am)
Friday, April 3
Departure
_ Plenary talk of 50 minutes.
Program current as of 1/26/98 and is subject to change.
* Session Chair; + Speaker invited, not yet responded. |
