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Biotech / Medical : Ligand (LGND) Breakout!
LGND 184.09-0.9%Dec 10 3:59 PM EST

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To: Flagrante Delictu who wrote (18532)4/3/1998 5:59:00 AM
From: Henry Niman  Read Replies (2) of 32384
 
Bernie, I had a chance to look at the uploaded table on LGND's pipeline ( home.att.net )and there are a few updates that are of interest.

I was a bit surprised to see a Targretin oral Phase II/III Breast Cancer trial listed. As you know, LGND has indicated that they were going to pursue breast cancer very aggressively, but the recent 10-K suggests that such a trial has already begun.

Another area of interest is the small molecule program with SBH using STAT technology. The hematopoietic growth factor group (and interferon agonists) is characterized as "lead compound selected" which suggests that they indeed to have compounds that work on humans (the G-CSF compound recently described at Lake Tahoe was mouse specific).

Finally, in the area of androgen antagonists, the category is in the "development candidate" category, indicating that the series is ready for IND filing. I wouldn't be surprised to see an NDA for prostate cancer filed by LGND, and a major alliance for cosmeceuticals and BPH.
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