Glory be! Looks like the conversions may be over -
Title of Shares to Proposed Maximum Proposed Amount of be Registered Amount Aggregate Price Per Maximum Registration Common Registered Share (1) Aggregate Fee (3) stock, par 6,250,000 (2) $1.61 Offering $2003 value $.01 Price per share $10,062,500 (1) Estimated solely for purposes of computing the registration fee pursuant to Rule 457(c). (2) Pursuant to Rule 416 under the Securities Act of 1933, any additional shares of Common Stock issued as a result of the anti-dilution provisions of the Certificate of Designation relating to the Preferred Stock pursuant to which the Common Stock will be issued are deemed to be registeredherewith. (3) Represents the sum of $1,884 originally paid in connection with the registration of 6,000,000 shares pursuant to Rule 457(a) and $119 to register 250,000 shares of the proposed maximum aggregate price per share. The Registrant hereby amends this Registration Statement on such date or dates as may be necessary to delay its effective date until the Registrant shall file a further amendment which specifically states that this Registration Statement shall thereafter become effective in accordance with Section 8(a) of the Securities Act of 1933 or until the Registration Statement shall become effective on such date as the Commission, acting pursuant to said Section 8(a), may determine. 2<PAGE> SUBJECT TO COMPLETION, DATED APRIL 3, 1998 6,250,000 Shares CYTOGEN CORPORATION COMMON STOCK This Prospectus relates to up to 6,250,000 shares of Common Stock, par value $.01 per share (the "Common Stock"), of CYTOGEN Corporation ("CYTOGEN" or the "Company"), which have been registered for sale from time to time by the selling stockholders named herein or their permitted transferees or successors (the "Selling Stockholders"). Any or all of the Common Stock being registered hereby may be sold from time to time to purchasers directly by the Selling Stockholders. Alternatively, the Selling Stockholders may from time to time offer the Common Stock through underwriters, dealers or agents who may receive compensation in the form of underwriting discounts, concessions or commissions from the Selling Stockholders and/or the purchasers of Common Stock for whom they may act as agent. To the extent required, the names of the Selling Stockholders, the number of shares of Common Stock to be sold, purchase price, public offering price, the name of any agent, dealer or underwriter and any applicable commission or discount or other items constituting compensation or indemnification arrangements with respect to a particular offering will be set forth in an accompanying Prospectus Supplement. The Company will receive no proceeds from sales by the Selling Stockholders of the Common Stock offered hereby. The shares of Common Stock to which this Prospectus relates are issuable to the Selling Stockholders from time to time upon conversion of or as dividends on certain securities received in the Private Placement (as defined herein). All Registration Expenses (as defined herein) incurred in connection with the registration of the Common Stock to which this Prospectus relates will be borne by the Company. The Company has agreed to indemnify the Selling Stockholders against certain liabilities, including certain liabilities under the Securities Act of 1933, as amended (the "Securities Act"), or to contribute to payments which the Selling Stockholders may be required to make in respect thereof. See "Plan of Distribution." The Common Stock is traded on the Nasdaq National Market under the symbol "CYTO." The last reported sale price of the Common Stock as reported by the Nasdaq National Market on March 31, 1998 was $2.16 per share. The Common Stock offered hereby involves a high degree of risk. See "Risk Factors" beginning on page 5 for a discussion of certain factors that should be considered by prospective investors. --------------------- THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION NOR HAS THE SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION PASSED UPON THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE. ----------------------
> SELLING STOCKHOLDERS -------------------- The following table sets forth certain information regarding the beneficial ownership of Common Stock by the Selling Stockholders as of April 2, 1998, and the number of shares of Common Stock covered by this Prospectus.<TABLE><CAPTION> Number of Shares of Number of Shares of Common Stock Beneficially Number of Shares of Common Stock Beneficially Name and Address Owned Common Stock Offered Owned Following the Stockholder Prior to the Offering (1) Hereby (2) Offering (3) ----------- ------------------------- ---------- ------------ # of Shares % of Class # of Shares % of Class ----------- ---------- ----------- ---------- <S> <C> <C> <C> <C> <C> Southbrook International Investments, Ltd. 2,499,767 4.36 2,566,237 4.47 0 c/o Trippoak Advisors, Inc.630 Fifth Avenue, Suite 2000New York, NY 10111 Westover Investments L.P. 914,579 1.60 927,873 1.62 0 777 Main Street, Suite 2750Fort Worth, TX 76102 Montrose Investments L.P. 1,371,869 2.39 1,391,810 2.42 0 777 Main Street, Suite 2750Fort Worth, TX 76102 Heracles Fund 438,076 .76 454,693 .79 0 Bank of Bermuda (Cayman) LimitedP.O. Box 5133rd Floor, British American Center Dr. Roy's Drive Georgetown, Grand CaymanCayman Islands, BWI Themis Partners, L.P. 438,076 .76 454,693 .79 0 c/o Promethean Investment Group L.L.C.40 West 57th Street, Suite 1520 New York, NY 10019 Brown Simpson Strategic Growth Fund, L.P. 175,230 .31 181,878 .32 0 152 West 57th Street, 40th Floor New York, NY 10019 Brown Simpson Strategic Growth Fund, Ltd. 262,845 .46 272,816 .47 0 152 West 57th Street, 40th FloorNew York, NY 10019 ----------------------------- 18<PAGE> (1) Includes (i) the number of shares of Common Stock issued or issuable upon conversion of shares of the Company's Series B Convertible Preferred Stock, assuming, with respect to unconverted shares, conversion at the formula price in effect on April 2, 1998 (which price will fluctuate from time to time based on changes in the market price of the Common Stock and provisions in the formula for determining the conversion price). The Series B Preferred Stock was issued by the Company to the Selling Stockholders in December 1997 in a transaction exempt from the registration requirements of the Securities Act of 1933 pursuant to Regulation D thereunder (the "Private Placement"). (2) In order to provide for (i) fluctuations in the market price of the Common Stock, (ii) provisions in the formula for determining the conversion price of the Series B Preferred Stock set forth in the terms thereof (see "Description of Series B Convertible Preferred Stock") and (iii) shares of Common Stock which may be issued in payment of dividends on the Series B Preferred Stock, the aggregate number of shares of Common Stock registered hereby exceeds the aggregate number of such shares issuable upon conversion of shares of the Series B Preferred Stock at the conversion price in effect on the date hereof. For each Selling Stockholder, the number in this column represents such Selling Stockholder's pro rata portion of the aggregate number of shares of Common Stock registered hereby. No Selling Stockholder may acquire more than 4.99% of the Common Stock unless they give the Company at least 65 days notice of the waiver of such restrictions.(3) Assumes sale of all shares offered hereby. PLAN OF DISTRIBUTION -------------------- The Selling Stockholders may, from time to time, sell all or a portion of the shares of Common Stock (the "Shares") on the Nasdaq National Market, in privately negotiated transactions or otherwise, at fixed prices that may be changed, at market prices prevailing at the time of sale, at prices related to such market prices or at negotiated prices. The Shares may be sold by the Selling Stockholders by one or more of the following methods, without limitation: (a) block trades in which the broker or dealer so engaged will attempt to sell the Shares as agent but may position and resell a portion of the block as principal to facilitate the transaction, (b) purchases by a broker or dealer as principal and resale by such broker or dealer for its account pursuant to this Prospectus, (c) an exchange distribution in accordance with the rules of such exchange, (d) ordinary brokerage transactions and transactions in which the broker solicits purchasers, (e) privately negotiated transactions, (f) short sales and (g) a combination of any such methods of sale. In effecting sales, brokers and dealers engaged by the Selling Stockholders may arrange for other brokers or dealers to participate. Brokers or dealers may receive commissions or discounts from the Selling Stockholders (or, if any such broker-dealer acts as agent for the purchasers of such shares, from such purchaser) in amounts to be negotiated which are not expected to exceed those customary in the types of transactions involved. Broker-dealers may agree with the Selling Stockholders to sell a specified number of such Shares at a stipulated price per share, and, to the extent such broker-dealer is unable to do so acting as agent for a Selling Stockholder, to purchase as principal any unsold Shares at the price required to fulfill the broker-dealer commitment to the Selling Stockholders. Broker-dealers who acquire Shares as principal may thereafter resell such Shares from time to time in transactions (which may involve block transactions and sales to and through other broker-dealers, including transactions of the nature described above) in the over-the-counter market or otherwise at prices and on terms then prevailing at the time of sale, at prices related to the then-current market price or in negotiated transactions and, in connection with such resales, may pay to or receive from the purchasers of such Shares commissions as described above. The Selling Stockholders may also sell the Shares in accordance with Rule 144 under the Securities Act, rather than pursuant to this Prospectus. 19<PAGE> The Selling Stockholders and any broker-dealers or agents that participate with the Selling Stockholders in sales of the Shares may be deemed to be "underwriters" within the meaning of the Securities Act in connection with such sales. In such event, any commissions received by such broker-dealers or agents and any profit on the resale of the Shares purchased by them may be deemed to be underwriting commissions or discounts under the Securities Act. From time to time the Selling Stockholders may engage in short sales, short sales against the box, puts and calls and other transactions in securities of the Company or derivatives thereof, and may sell and deliver the Shares in connection therewith or in settlement of securities loans. If the Selling Stockholders engage in such transactions, the Conversion Price may be affected. From time to time the Selling Stockholders may pledge their Shares pursuant to the margin provision of their respective customer agreements with their brokers. Upon a default by the Selling Stockholders, the broker may offer and sell the pledged Shares from timeto time. The Company is required to pay all fees and expenses incident to the registration of the Shares, including fees and disbursements (not to exceed an aggregate of $10,000) of counsel to the Selling Stockholders. The Company has agreed to indemnify the Selling Stockholders against certain losses, claims, damages and liabilities, including liabilities under the Securities Act. DESCRIPTION OF CAPITAL STOCK ---------------------------- As of the date of this Prospectus, the Company's authorized capital stock consists of 89,600,000 shares of Common Stock, par value $0.01 per share, and 5,400,000 shares of preferred stock, $0.01 per share. Pursuant to the Certificates of Designation for the Series A Preferred Stock (as defined below) and for the Series B Preferred Stock, 1,000 shares of Series A Preferred Stock and 750 shares of Series B Preferred Stock, respectively, have been authorized for issuance. The description below is a summary of all material provisions of the Company's Common Stock and preferred stock. Common Stock------------ The holders of Common Stock are entitled to one vote per share on all matters voted on by the stockholders, including elections of directors. Except as otherwise required by law or as provided in any resolutions adopted by the Board with respect to the preferred stock of the Company, the holders of shares of Common Stock will exclusively possess all voting power. Subject to the preferential rights, if any, of holders of any then outstanding preferred stock, the holders of Common Stock are entitled to receive dividends when, as and if declared by the Board of Directors of the Company out of funds legally available therefor. The terms of the Common Stock do not grant to the holders thereof any preemptive, subscription, redemption, conversion or sinking fund rights. Subject to the preferential rights of holders of any then outstanding preferred stock, the holders of Common Stock are entitled to share ratably in the assets of the Company legally available for distribution to stockholders in the event of the liquidation, dissolution or winding up of the Company. As of February 27, 1998, 53,831,046 shares of Common Stock were issued and outstanding, and 1,260,000 shares of Common Stock were reserved for issuance upon the exercise of certain outstanding warrants and approximately 6,230,102 shares were reserved for issuance pursuant to stock option plans and Employee Stock Purchase Plans. The Company has issued to Dow and Elan, warrants to purchase an aggregate of 1,260,000 shares of Common Stock at prices ranging from $8.40 to $14.00 per share. In connection with the Company's acquisition of an exclusive license from Dow, CYTOGEN issued to Dow two warrants to purchase an aggregate of 260,000 shares of Common Stock at $12.50 per share. The remaining warrant is held by Elan. See "Description of Capital Stock Preferred Stock" for a description of the Elan warrant. 20<PAGE> The Certificate of Incorporation and Bylaws of the Company contain certain provisions which may have the effect of delaying, deferring, or preventing a change of control of the Company. See "Risk Factors Anti-takeover Considerations". In addition, the Board generally has the authority, without further action by stockholders, to fix the relative powers, preferences, and rights of the unissued shares of preferred stock of the Company. Provisions which could discourage an unsolicited tender offer or takeover proposal, such as extraordinary voting, dividend, redemption, or conversion rights, could be included in such preferred stock. For a description of certain rights which may also affect a change-in-control transaction, see "Description of Capital Stock Preferred Stock."Preferred Stock--------------- Pursuant to the Certificate of Incorporation, the Company has the authority to issue up to 5,400,000 shares of preferred stock, $0.01 par value per share, in one or more series as determined by the Board of Directors of the Company. The Board of Directors of the Company may, without further action by the stockholders of the Company, issue one or more series of preferred stock and fix the rights and preferences of such shares, including the dividend rights, dividend rates, conversion rights, exchange rights, voting rights, terms of redemption, redemption price or prices, liquidation preferences and the number of shares constituting any series or the designation of such series. Shares of any series of preferred stock of the Company may be represented by depositary shares evidenced by depositary receipts, each representing a fractional interest in a share of preferred stock of such series and deposited with a depository. The use of this mechanism could increase the number of interests in preferred stock issued by the Company. The rights of the holders of Common Stock will be subject to, and may be adversely affected by, the rights of holders of preferred stock issued by the Company in the future. In addition, the issuance of preferred stock could have the effect of making it more difficult for a third party to acquire, or of discouraging a third party from attempting to acquire, control of theCompany. Series A Preferred Stock------------------------ Pursuant to the Certificate of Designations, Powers, Preferences and Rights of the Series A Convertible and Exchangeable Preferred Stock (the "Series A Certificate of Designation"), 1,000 shares of Series A Preferred Stock (the "Series A Preferred Stock"), with a liquidation preference of $5,000 per share, have been authorized for issuance. Of these authorized shares, all have been issued and are outstanding. All of the 1,000 shares of Series A Preferred Stock were purchased by Elan for $5.0 million in September 1996. The proceeds from the sale of the Series A Preferred Stock, along with $5.0 million in proceeds from the sale of Common Stock to Elan were used to fund the formation of Targon Corporation, a majority-owned (99.75%) subsidiary of the Company. Targon focuses exclusively on the rapid development, registration, manufacturing and commercialization of oncology products. The Series A Preferred Stock held by Elan could, at Elan's option be either (i) exchanged for a portion of the Company's interest in Targon which declines from 50% to 35%, depending on the time of the exchange, which exchange may not occur later than September 30, 2001 or (ii) converted into shares of Common Stock of CYTOGEN. On March 31, 1998, Elan exchanged the Series A Preferred Stock for a portion of the Company's interest in Targon. Elan is entitled through March 31, 2003 to exercise a warrant to purchase up to 1 million shares of CYTOGEN Common Stock, at an exercise price per share which escalates from $8.40 to $14 over the life of the warrant. Elan's right to convert the Series A Preferred Stock into shares of common stock of CYTOGEN expired on exercise of this exchange right. The Series A Preferred Stock is no longer outstanding. Description of Series B Convertible Preferred Stock --------------------------------------------------- The 750 shares of Series B Preferred Stock were issued by the Company to the holders of Series B Preferred Stock (the "Series B Holders") in the Private Placement. Each share of Series B Preferred Stock has a par value of $.01 per share and a stated value of $10,000 per share (the "StatedValue"). 21<PAGE> Pursuant to the Certificate of Designation relating to the Series B Preferred Stock (the "Series B Certificate of Designation") the Series B Holders are entitled to receive, when, as and if declared by the Board of Directors of the Company (the "Board of Directors"), out of funds legally available therefor, cumulative dividends at a rate of 6% of the Stated Value per share per annum, payable, at the option of the Company, in cash or shares of Common Stock (subject to certain limitations). Dividends on the Series B Preferred Stock shall be deemed to accrue from the date of original issue of the Series B Preferred Stock, whether or not earned or declared and whether or not there are profits, surplus or other funds of the Company legally available for the payment of dividends. Accrued dividends on the Series B Preferred Stock shall be paid on the date such Series B Preferred Stock is converted, but the Company shall have the option to pay dividends in cash or shares of Common Stock and more frequently as and when declared by the Board of Directors. The Series B Certificate of Designation does not provide for a sinking fund. The Series B Certificate of Designation prohibits the repurchase by the Company of, or the payment or declaration of any dividends with respect to, any securities of the Company junior to or pari passu with the Series B Preferred Stock (with certain exceptions). Except as may be required by law and except with respect to certain actions which may adversely affect the Series B Holders, the Series B Holders are not entitled to vote on any matter submitted to a vote of stockholders of the Company. The Series B Preferred Stock ranks senior with respect to rights on liquidation, winding-up and dissolution of the Company to the Company's Common Stock. Upon any voluntary or involuntary liquidation, dissolution or winding-up of the Company, holders of Series B Preferred Stock will be entitled to receive $10,000 per share, plus accrued and unpaid dividends, before any distribution is made on the common stock or any preferred stock of the Company ranking junior as to liquidation rights to the Series B Preferred Stock. The Series B Holders have the right to convert shares of Series B Preferred Stock into common stock at a conversion price (the "Initial Conversion Price") equal to the lesser of (a) $3.4575 and (b) at a discount of up to 15% of the average of four closing bid prices chosen by the Series B Holders during the twenty-five trading days prior to notice of conversion, which discount is initially 5% and shall increase by 5% on the first day of the two months subsequent to the Original Issue Date of the Series B Preferred Stock. If, however, the average per share market value for the five day trading period immediately preceding the conversion date exceeds the Initial Conversion Price by 180%, then the conversion price otherwise applicable to such conversion shall be increased by an amount equal to 50% of the difference between the average per share market value for the five day trading period immediately preceding the conversion date and the Initial Conversion Price. The Conversion Price may be adjusted under certain circumstances, including the failure by the Company to file a registration statement with the Securities and Exchange Commission (the "Commission") for the underlying shares into which the Series B Preferred Stock is convertible, the failure of such registration statement to be declared effective by the Commission within certain time periods, suspension of trading of the Company's common stock or upon the occurrence of certain other events. If on the date of conversion, the conversion price then in effect would result in the number of shares issuable in connection with such conversion (including the conversion shares issued in respect of payment of dividends) equalling or exceeding 20% of the number of shares of Common Stock outstanding on the Original Issue Date, the Company is, under certain circumstances, required to obtain the approval of a majority of shareholders to authorize such issuance. If such approval is not obtained certain penalties may apply. The Series B Holders have agreed that in no event shall any such Series B Holder be entitled to convert any shares of Series B Preferred Stock if the issuance of shares of Common Stock upon a proposed conversion, when the shares to be so issued are counted together with other shares of common stock beneficially owned by such Series B Holder would result in a Series B Holder beneficially owning more than 22<PAGE> 4.999% of the outstanding shares of Common Stock. The Series B Preferred Stock is convertible at the option of the Company three years from the Original Issue Date. All outstanding and unconverted shares of Series B Preferred Stock are redeemable on the third anniversary of the Original Issue Date at a price per share equal to the product of (1) the average per share market value for the five trading days immediately preceding (i) the third anniversary of the original issue date or (ii) the date of payment in full by the Company of the redemption price, whichever is greater, and (2) the Stated Value plus accrued but unpaid dividends not paid in Common Stock divided by the Conversion Price for the Series B Preferred Stock calculated on the third anniversary of the Original Issue Date. |