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Biotech / Medical : Ligand (LGND) Breakout!
LGND 205.55-1.3%Nov 12 3:59 PM EST

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To: Bryce Elkins who wrote (18702)4/6/1998 4:23:00 PM
From: Henry Niman  Read Replies (1) of 32384
 
BLe, LGND's closing ask price was 15 7/16, which is close to the price you paid. I think it very briefly hit 15 5/16, but even when the bid fell to 15 1/8, the ask was usually at 15 3/8. The trading was heavily on the retail side, and I did get a chance to review the Inquirer story on Tamoxifen.

It looks like about twice as many women develop blood clots on their lungs as the number that don't develop breast cancer and about 1/2 that number get endometrial cancer.

Other's also develop uterine bleeding, so it's clear that there is considerable risk associated with the treatment. I'm not sure about the bleeding, but Targretin does help the endometrial problem in animal models.

Joe Kernan just indicated that ZEN was up 10 today and even LLY got a boost because Evista works the same way as Tamoxifen (as does Droloxifene, CP-366,156, and TSE424, all of which involve LGND).
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