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Biotech / Medical : Ligand (LGND) Breakout!
LGND 200.79-0.2%Nov 14 9:30 AM EST

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To: squetch who wrote (18878)4/8/1998 9:03:00 AM
From: Henry Niman  Read Replies (1) of 32384
 
Stan, I think that there is a distinct limit on the amount of "experimenting" that they can do with patients. I suspect that when the start seeing "moderate" adverse effects, they consider that the maximum dose. On several of their protocols, this dose is patient specific (they gradually increase the dose until they start seeing side effects). I think that the "agressiveness" in increasing doses is somewhat dependent on the severity of the conditions. In terminal cancer patients, they are more aggressive in the dosing (I think that they go up to 600 mg).
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