Cistron is largely a competitor to companies like R&D Systems (Techne), PharMingen (private) and BioSource Intl (BIOI). Take a look at the market cap of BIOI and the premium relative to cash in-hand, and you may develop an appetite to again consider it for short-term.
Almost any immunologist can tell you that they have a moderately effective marketing effort. I have high respect for their cytokine assays, and their on-going reagents business is, IMO, deserving of consideration. They will now have big bucks to promote their products. They have an outstanding judgement against PeproTech, a company that I know well, for $2.7 million. PeproTech filed for bankruptcy and is still functioning. This will mean more money coming to CIST, the only question is how much and how soon.
IL-1 and IL-1-based assays sell very well, world-wide. If CIST is now free to go after other providers, will it mean additional royalties and potential damages? Their 10-K is well worth the read.
To stimulate your appetite for reading, CIST has license agreements with GTI (now Sandoz) and Biotech Australia Pty (a "jointly owned subsidiary of Hoechst A.G. and Hoechst Australia Ltd.") for therapeutics. It looks like the GTI agreement is rather IMNR-like, except using IL-1 instead of TNF in a recombinant cancer vaccine. The "Hoechst" agreement looks more interesting (to me), and involves a plasminogen activator inhibitor. The promise of any such agreement, of course, involves wording...... no way you're going to put a PAI inhibitor into people for cancer therapy unless you can (1) do it with a small molecule, and (2) target it.
CIST is a legitimate company that has effectively marketed, for some time, a small variety of of cytokines and assays for such. Given 27 million shares out, cash flow from a respected reagents business, and $21 million plus out in guaranteed cash coming in, I'd say that companies that currently OEM IL-1 would be interested in CIST. Obviously, while I know this industry very well, I do not yet know about hidden liabilities that CIST might have. I can't emphasize this enough....... it requires research beyond that which I have done to date.
Rick |