Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 203.18

-1.4%

Nov 28 9:30 AM EST

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To: Henry Niman who wrote (19427)	4/22/1998 5:46:00 PM
From: squetch	Read Replies (2) of 32384

Is LG268 a TZD? Thanks for the ABC news; I would prefer you checked out Cell. Two articles coauthored by Evans on PPAR-y. A minireview of the articles as well by Bruce Spiegelman who coauthored this paper. jci.org I read about LG100153 in another paper. It appeared in a table labeled Relative affinities of Retinoids for each receptor (all 6 RAR/RXR receptors) It said it was RXRalpha,beta, gamma agonist. Its binding affinity for RAR-a was >10,000 vs. 9-cis at 7 and ATRA at 15.

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