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Biotech / Medical : Chromatics Color Sciences International. Inc; CCSI
CCSI 29.42+0.3%3:59 PM EST
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To: STLMD who wrote (1972)5/2/1998 6:48:00 PM
From: JanyBlueEyes  Read Replies (2) of 5736
 
As to every infant being monitored. If you think that means a bili is done, then you're wrong. If you think that a Colorimetric test will now be done on every child, you're very wrong, and let me assure you a colorimetric test at 24 hours of life in a baby going home from hospital is not going to be done.

Here is an abstract from ncbi.nlm.nih.gov
From Dec '96.
This data was based on healthy term infants only - no preemies.
It does not say what jaundice meter was used for screening nor does it point out the importance of the non-invasive aspect of the device.

==========

Clinical impact of transcutaneous bilirubinometry as an adjunctive screen for hyperbilirubinemia.

Dai J, Krahn J, Parry DM

Department of Clinical Biochemistry, St. Boniface General Hospital, Manitoba, Canada.

OBJECTIVE: To determine what the clinical impact would be of implementing a jaundice meter for use in a busy neonatal service as an adjunctive screening tool for hyperbilirubinemia.

DESIGN AND METHODS: Test utilization data was collected for a 6-month period to determine how neonatal bilirubin was utilized in this hospital. The jaundice meter was evaluated in a study population of healthy term infants. The performance characteristics of the meter and the test utilization data were used to predict the clinical impact a meter could have on screening for hyperbilirubinemia.

RESULTS: Utilization data indicated that about 60% of all single bilirubin neonatal testing (i.e., bilirubin only ordered) was done by normal nurseries.

A jaundice meter cutoff decision reading of 17 was shown to have a sensitivity of 100% and a specificity of 68% for hyperbilirubinemia (> 260 mumol/L) in a study population of healthy term infants.

From this data, it was estimated that use of a jaundice meter could eliminate 43% of the single (i.e., not combined with other tests) bilirubin tests done on healthy term neonates with no prior exposure to phototherapy.

This constitutes an overall 20% reduction in bilirubin testing in normal nurseries when testing done on babies exposed to phototherapy and combined bilirubin testing are taken into consideration.

Additionally, it was shown that there would be an improvement of 9% in the prediction of hyperbilirubinemia without loss of 100% sensitivity.

CONCLUSION: Use of a jaundice meter in normal nurseries as an adjunctive screening tool enhances patient care by reducing the overall blood procurement rate in normal nurseries by 20% and increasing screening efficiency for significant hyperbilirubinemia by 5%.
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