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Biotech / Medical : Ligand (LGND) Breakout!
LGND 195.05-0.4%3:59 PM EST

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To: bob zagorin who wrote (21061)5/18/1998 5:33:00 PM
From: Henry Niman  Read Replies (1) of 32384
 
LGND issued two press releases this evening.

Two LGD1550 studies showed that it had fewer side effects than other retinoids and it did not induce its own metabolism. Phase II trials in head & neck and cervical cancers are planned.

The second abstract was on the AIDS consortium Phase II data for treating KS with oral Panretin. A 37% response rate was achieved (identical to LGND's study on oral Panretin for KS). Responding patients were on PIs but had high HIV levels. There was no relationship between Panretin effect and HIV levels.

NDA for topical Panretin for KS was slated for filing "soon".
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