Corixa [CRXA] - cancer vaccines Message Board

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Biotech / Medical : Corixa [CRXA] - cancer vaccines

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To: scaram(o)uche who wrote (7)	5/27/1998 12:44:00 AM
From: Miljenko Zuanic	Read Replies (1) of 222

Rick: Any idea how Corixa TB vaccines differ from old bacilli Calmette-Guerin (BCG) type or any other in development? How potent anti-tuberculosis vaccine defer from regular one? In contest of the multi-drug resistant strains of Mycobacterium tuberculosis, which is today major problem. From literature research I didn't find are this CRXA TB antigens derived from secreted proteins or are parts of bacterial membrane structure. BTW, it was bad luck (or FDA regulations) that Corixa had to tried first naked anti-HER-2/neu vaccine in PI, and than incorporate core technology of the microsphere delivery system and their own adjuvant, LeIF, which give much better humaral and cellular responses. mz PS: Please, keep in mind that you are dealing with complete amateur in this field.

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