Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 181.46

-2.4%

Feb 12 3:59 PM EST

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To: Machaon who wrote (21525)	5/28/1998 6:43:00 PM
From: Henry Niman	Read Replies (1) of 32384

Bob, Having an approved product goes a long way toward speeding up subsequent trials. The purpose of Phase I trials is to test safety. Phase II is to determine the optimal concentration. Phase III is to prove that the drug is effective and safe. Use of an approved product by patients goes a long way toward proving safety. After approval, most of the effort is on efficacy for new target populations. LGND traditionally has done small trials to identify appropriate target populations. When products are approved, they can be expanded into new populations before Phase III trial are completed (through off label use) and Phase III trials can go quicker.

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