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Biotech / Medical : Biotime-Nasdaq's best kept secret?
BTIM 0.00010000.0%Nov 5 1:26 PM EST

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To: Jim Roof who wrote (999)6/9/1998 10:30:00 AM
From: mesaone   of 1432
 
this is pennsylvania merchant groups buy recommendation dated june 3rd. analayst is michael martorelli.

we continue to recommend btim as an attractive speculation, but only for investors with a strong tolerance for
mischief and uncertainity. at the end of the day, it will be the FDA (not individual physicians or investors writing
threads on intenet chat roms) that will decide 1. whether to accept btim's new drug application for its lead
product hextend, and 2. whether the product is safe and effective enough to be approved. further, itw ill be the
hospital and anesthesoiologist customer base of abbott las (not individual physicians contacted by reporters or
analysts) that will decide how successful the product will be on the marketplace. in the absence of any hard data
on any of those three important issues, we believe the stock will continue to a volatile playtoy of both the longs
andthe shorts. Indeed facts will determine the outcome of the BTIM investment story. we remain confident in the
company's management, its business plan, and in the relative attractiveness of it's stock.
BTIM's management and its regulatory consultant communicated with fda personnel and recieved their
permission to forgo phase 1 and II trials of hextend. permission to proceed with the 117 patient phase III trials
was based on the per-existing knowledge of Hexten's components and widespread clinical use of the drug
substance hetrastarch. It would be naive to assume that any particular company could never misinterpret the fds's
comments regarding a clinical trial program, or that every company that completed a phase III trial completed it
correctly. On its face, however, the phase III trial that is the basis of the hextend NDA does seem to have been
completed satisfactorily, i.e. no inordinate number of patient dropouts and no large gaps in the data collected.
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