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Biotech / Medical : SANGUINE CORP. (SGNC)
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To: Profiteer who wrote ()6/15/1998 1:48:00 AM
From: sdheart   of 5402
 
HELPS TO VISUALIZE THE HEART--AND SAFE!!!

Nippon Rinsho 1998 Apr;56(4):914-920

[Myocardial contrast echocardiography from peripheral venous injection: the potential for
detection of myocardial perfusion abnormality].

[Article in Japanese]

Matsumura M

Saitama Heart Institute, Saitama Medical School.

Myocardial contrast echocardiography is a useful method for clinical evaluation of
myocardial perfusion abnormality in ischemic heart disease. However, this method has a
limitation in selection of patients because it is necessary to inject the contrast agent
directly into the coronary artery in a catheterization room to obtain the image of
myocardial opacification. Recently several echo contrast agents that have the potential for
myocardial opacification after intravenous injection have been developed. These agents
consist of perfluorocarbon gas filled-microbubble coated by a stabilizing surfactant. It's
persistence is longer in air filled-microbubble such as Albunex. Safety of contrast agent
and highly efficacy for myocardial opacification, no significant changes in parameters of
cardiopulmonary function and hemodynamics are reported both in animal and human
studies. In future contrast myocardial echocardiography with intravenous injection offers
the potential for reliable and noninvasive assessment of perfusion in myocardial infarction
before and after therapeutic interventions.
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