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Biotech / Medical : Agouron Pharmaceuticals (AGPH)

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To: Steve Fancy who wrote (4506)6/17/1998 11:36:00 AM
From: Steve Fancy  Read Replies (2) of 6136
 
Immune Response Corp Begins
Clinical Trial Of HIV Drug

Dow Jones Newswires

CARLSBAD, Calif. -- Immune Response Corp.
(IMNR) began a double-blind, placebo-controlled
clinical trial of Remune, an HIV drug.

Immune Response and Agouron Pharmaceuticals Inc.
(AGPH) are developing Remune.

In a press release Wednesday, the company said the
one-year trial will test the drug's effect on HIV-specific
immune responses in HIV-1 patients who have been
treated with highly active antiretroviral therapy, or
HAART.

The company will enroll HIV-infected patients who have
undetectable viral load after taking HAART for at least
six months. It will treat the patients with Remune or the
placebo in combination with HAART.

According to Immune Response, scientists conducting
the trial previously have shown a correlation between
HIV-specific T-cell proliferation and the successful
control of virus replication in certain HIV patients.

The trial will examine whether inducement of such
immune responses can be increased in Remune-treated
individuals who are taking HAART as well.
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