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Biotech / Medical : Agouron Pharmaceuticals (AGPH)

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To: Todd N who wrote (4515)6/17/1998 2:15:00 PM
From: John Metcalf   of 6136
 
Todd, Monsanto's G.D.Searle website has information on each stage of the drug development process, along with a drug development "game", or simulation.

However -- data on how many drugs progress to the next phase of clinical trials is skewed by companies that take compounds with very little promise into the next round in order to keep the pot boiling while they look for something else.

In this case, Agouron believes that efficacy is equal to the existing treatment without having to administer toxic levels of drug. The clinical rationale makes sense, and may be better when drug is given to people who are not in advanced stages of cancer where neovascularization has already occurred.
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