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Biotech / Medical : Vivus: into single digits

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To: MIKE DUBIS who wrote (611)6/17/1998 11:46:00 PM
From: BigKNY3  Read Replies (1) of 1016
 
Here is an update of ED specification based on Internet posts and press releases.

Highlights are are follows:

-Total Viagra prescriptions have now surpassed 2 million since launch
-Viagra new Rxs and refill Rxs for the week ending June 5th were impressive ....given that over 4,000 urologists were attending the AUA meeting in San Diego.
-Viagra refill Rxs were very impressive with the important Refill/New Rx ratio moving up to 32.9% .

Note: The Memorial Day holiday had a negative impact on the 5/29/98 data.

BigKNY3
__________________________________________________________

ED New RXs
Correlation: -0.903
.....................................................% Share.......% Share
......Week....Viagra........MUSE........ Viagra.........MUSE
..... Ending...New Rxs....New Rxs.....New Rxs.....New Rxs
10..6/05/98....192,585.....2,035.........99.0%.........1.0%
9... 5/29/98...161,405.....2,097......... 98.7%.........1.3%
8... 5/22/98...236,525.....2,344......... 99.0%.........1.0%
7....5/15/98....262,566....2,373......... 99.1%........ 0.9%
6... 5/8/98......278,715....2,588......... 99.1%.........0.9%
5... 5/1/98......269,842....2,945......... 98.9%.........1.1%
4... 4/24/98.....207,868 ..3,524......... 98.3%.........1.7%
3... 4/17/98.....113,134....4,609........ 96.1%..........3.9%
2....4/10/98 ......36,263... 6,716........84.4%.........15.6%
1....4/3/98............ 546... 7,998...........6.4%........93.6%
0....3/27/98...... ...... 0... 9,593 ..........0.0%.......100.0%
Total .............1,759,449..37,229

Avg Post Viagra.175,945....3,723
Avg. 1997.........................12,594
...% Chg Post/1997..............-70.4%
________________________________________
ED Refill RXs
Correlation: -0.920
............................................................% Share......% Share
......Week...Viagra.............MUSE...........Viagra..........MUSE
......Ending..Refill Rxs.........Refill Rxs......Refill Rxs....Refill Rxs
10..6/05/98....63,323..............2,755.......95.8%..........4.2%
9....5/29/98....49,452..............2,737....... 94.8%........ 5.2%
8....5/22/98....45,972...............3,026 ......93.8%......... 6.2%
7....5/15/98 ...35,100...............3,078..... 91.9%..........8.1%
6....5/8/98......24,700...............3,277......88.3%......... 11.7%
5....5/1/98.......16,429............. 3,659......81.8%......... 18.2%
4....4/24/98.......7,508..............3,824......66.3%......... 33.7%
3....4/17/98.......2,109..............4,290......33.0%......... 67.0%
2....4/10/98 .........429..............4,677..... 8.4%........... 91.6%
1....4/3/98...............0...............5,031.....0.0%...........100.0%
0....3/27/98.............0...............4,873..... 0.0%...........100.0%
Total..............245,022 ...........36,354
Avg Post Viagra..24,502............3,635.....84.4%......... 15.6%
Avg. 1997...................................3,278
% Chg Post/1997.........................10.9%
_____________________________________________________

ED Total Rxs
Correlation: -0.938
....................................................................% Share........... % Share
........Week................. Viagra...... MUSE...........Viagra........MUSE
........Ending...............Total Rxs....Total Rxs.....Total Rxs............Total Rxs
10..6/05/98..............255,908......4,799..............98.2%.....1.8%
9....5/29/98..............210,857......4,834............. 97.8%.....2.2%
8....5/22/98 ............ 282,497......5,370............. 98.1%.....1.9%
7....5/15/98............. 297,666......5,451............. 98.2%.....1.8%
6....5/8/98............... 303,415......5,865............. 98.1%.....1.9%
5....5/1/98............... 286,271......6,604............. 97.7%......2.3%
4....4/24/98............. 215,376......7,348............. 96.7%......3.3%
3....4/17/98............. 115,243......8,899..............92.8%.......7.2%
2....4/10/98 ...............36,692.....11,393............76.3%.......23.7%
1....4/3/98.......................546.....13,029..............4.0%......96.0%
0....3/27/98 .............. .........0.....14,466............ 0.0%.....100.0%
Total......................2,004,471.....88,058.
..... Avg Post Viagra ..200,447......7,359..............96.5%.......3.5%
......Avg. 1997............................15,872
......% Chg Post/1997....................-53.6%

______________________________________________________

ED Ratio: Refill Rxs/New Rxs

......................... Viagra.............MUSE
........Week............ % refills/.....% refills/
........Ending............New Rxs.........New Rxs
10..6/05/98...........32.9%.....135.4%
9....5/29/98............30.6%....130.5%
8....5/22/98............19.4%....129.1%
7....5/15/98 ...........13.1%....129.7%
6....5/8/98................8.9%....126.6%
5....5/1/98................6.1%....124.2%
4....4/24/98..............3.6%....108.5%
3....4/17/98 .............1.9%......93.1%
2....4/10/98 .............1.2%......69.6%
1....4/3/98 ............. 0.0%.....62.9%
0....3/27/98............ ............ 50.8%

..... Avg Post Viagra ..13.9%...97.6%
..... Avg. 1997.......................26.0%

Notes

Some suggestions on what to look for:

-New Rxs: The key to the health of a new product. Look for volume, market share and growth trends. Viagra New Rxs are expected to plateau and decline due to heavy initial trial usage. Holidays and major specialty conventions (such as the AUA Meeting) will effect weekly totals.

-Refill Rxs: An important indicator of the efficacy and toleration of a new product particularly one for prn therapy such as ED. These patients will not refill a product that is not working or is causing adverse reactions.

-Refill/New Rx Ratio: Another indicator of a product's success. After an initial launch period of 4-6 months, a successful new product should have a refill ratio of at least 50%. Conversely, a product with a refill ratio of less than 50% after 4-6 months may not have been viewed as effective, well-tolerated, or available.

In addition, a ratio of greater than 110% may result from a sharp decline in new specification due to alternative new therapies ....while the remaining satisfied patients continue to refill their Rxs. If this ratio is significantly higher than historical norms, the product may be in trouble.
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