Agouron Pharmaceuticals (AGPH) Message Board

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Biotech / Medical : Agouron Pharmaceuticals (AGPH)

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To: scaram(o)uche who wrote (4676)	7/1/1998 9:25:00 AM
From: Peter Singleton	Read Replies (3) of 6136

I did an altavista search KNI-272 (Japan Energy's 1st generation PI). There's a fair amount of information (albeit sketchy) on the compound. I don't have time this morning to post it, but a quick scan indicates the compound was developed around the time the currently marketed PIs were, showed some modest promise, but in the early clinical work it developed resistance in the same way as the other PIs, and wasn't as potent. Japan Energy and their collaborators went back to the drawing board, and AGPH has licensed their follow-on compound ..

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