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Biotech / Medical : PFE (Pfizer) How high will it go?
PFE 24.99-0.1%Dec 30 3:59 PM EST

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To: DaiS who wrote (3843)7/1/1998 9:54:00 AM
From: Perry  Read Replies (1) of 9523
 
<<Well I have to admit that I have not seen nor studied the Pfizer reports to the regulators, but I think that the
scientific publications to not provide information as to whether interactions involving the group categorisations
are significant or not - correct me if I am wrong. I would like to see and have time to study the full evidence.>>

When PFE originally got FDA approval there was a detailed report regarding the clinical results for Viagra on, I believe, the FDA site. I unfortunately do not have the report. Can somebody else possibly steer DaiS in the right direction?

<<On this specific point, there is alternative non-statistical approach. You can take each man that has
died, do an autopsy and a scientific investigation of this individual to establish precisely why he died -
a mechanistic approach for this individual.>>

I would be very surprise if autopsies were not conducted on at least some of the individuals that have died. I am not a coroner but I assume that any suspicious death(s) is examined in this way. In fact I recall that autopsies were done on some individuals and nothing was found to suggest a causal link to Viagra.

<<The approach could involve theoretical considerations of
the effect of the drug given it's structure - is it a poison - and so on.>>

If your talking about overt toxicity in the form of liver necrosis etc.. I don't think Viagra has ever been implicated as a cytotoxic agent, as evidenced by increases in blood liver enzyme (ALT etc..) levels.

I still think the numbers speak for themselves and continue to support Viagra as a safe and efficacious drug that is obviously helping 10000s of men.

Perry
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