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Biotech / Medical : XOMA. Bull or Bear?
XOMA 32.18-0.4%12:59 PM EST

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To: Robert K. who wrote (6612)7/2/1998 8:03:00 PM
From: aknahow  Read Replies (1) of 17367
 
Interesting article on TSC or thestreet.com by Jessie Eisinger on PGNS. Free trial available and an actual subscription is less than $70 per year.

A small part of the story is pasted here:

Like other doctors, Seilheimer worries that chronic use of high doses of tobramycin
via TOBI will cause bacteria to develop resistance to the drug, leaving the antibiotic
ineffective. While clinical trials haven't yet revealed resistance problems, "everyone
feels you're going to have increased resistance," Seilheimer says.

In addition, some doctors say they don't plan to use TOBI to treat chronically ill
patients. Instead, they'll only use it on patients who develop complications from
their bacterial infections. Dr. David Orenstein, of Children's Hospital in
Pittsburgh, estimates that he's treating about 5% to 10% of his patients with
TOBI. Of those, he's treating just 30% chronically. The rest get the drug only when
they have "acute exacerbations," or serious infections.
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