Rosemary, LGND continues to draw from the Pharms for its senior management. When they brought in AHP's Vice President, I thought that it was a signal for a takeover or a spin-out. LGND made a series of announcements all year that increased the relationship between LGND and AHP. Their alliance is very broad (women's health) and AHP is looking to protect its market share (AHP's Wyeth-Ayerst sells Premarin, a $1 Billion drug for Hormone Replacement Therapy, and to a less extent, osteoporosis). LGND's new hire was in charge of that program (which is trying to hold off the generics). The number of estrogen applications continues to grow (Alzheimer's, memory, baldness, etc). LGND's management in that area seems well positioned to make a major push (AHP has licensed progesterone agonists amd antagonist, they expanded the estrogen program by folding in some of the compounds AHP was initially developing independently, and they have an extensive tissue specific program). More recently LGND has brought in senior management from PNU. I think this is preparation for a major sales force to sell LGND's retinoids which were developed in-house (they split Panretin with AGN, but Targtretin is all LGND). Senior management is yet another strength of LGND.
Henry |