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Biotech / Medical : Ligand (LGND) Breakout!
LGND 206.84+3.8%Nov 24 3:59 PM EST
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To: RevMikeB who wrote (23000)7/13/1998 8:39:00 AM
From: Biotech Jim  Read Replies (2) of 32384
 
Small molecule agonists do not have to be orally bioavailable to be blockbusters. Of course it helps, but how many protein therapeutics are orally active? Also, the cost of goods will a lot less.

Well, we go from a question I raised several months ago to a Science paper. I guess the data I like most is that the compound appears to be a full agonist (fig. 6), but not according to fig. 5. Does it block natural G-CSF activity?

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