Richard,
I appreciate your efforts to keep the thread going these days. It is
somewhat frustrating to see the bioetchs starting to get hot, but PRLN
still in the doldrums.
Several thoughts...
It may be indeed difficult to conduct trials if the drug is already
on the market as a dietary supplement. For example, the cancer
patients, hoping to be cured, may go out and take even more drug
than that given in the trial, making the control of the dose
regimen problematic. It can be done of course, but it will make
control over the trials more difficult.
I am wondering about the Phase I results for PN355. As
I recall, there were only 10 patients enrolled for a 30-day study that
started way back in Jan, I think. Why haven't they disclosed the
results? Remember, the purpose of Phase I is to test for safety
and NOT for efficacy. The finding is either PN355 is safe or that
it is not. OF course, we all expect that it is safe since it has been
used for millenia, et etc... So why not disclose the data? Either
PN355 is not safe (very unlikely), or something came up that they
are not yet ready to reveal. Just a wild speculation, but sometimes
even Phase I results give an indication of drug efficacy...
I believe that PRLN is very safe to buy at its current level. I wish
I had the cash to buy up more at this time! Is anyone else increasing
their position?
By the way, a friend of my Mom has cancer and is willing to get involved in
experimental therapies. For example, she is just finishing in a study
of Genentech's anti-Her2 anitbody (Phase III). Anyway, I told her about Paracelsian's
AndroCar and she asked her doctor about it. Her doctor told her that
he knew of it but that it was only a dietary, and not a
therapeutic drug. It seems to me that her doctor is not completely
informed about Paracelsian, and maybe I should call him about it.
I was wondering what doctors out there are hearing about Paracelsian
and the opinions they are forming.
Rick |
