Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 201.14

+0.2%

3:38 PM EST

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To: Henry Niman who wrote (23308)	7/17/1998 3:35:00 PM
From: Lel H	Read Replies (2) of 32384

Henry, I posted the following on another board, so I'm not sure if you saw it: Just a few quick questions regarding Ligand's pipeline with reference to the recent Science report. Based on the pipeline chart on your website, it appears that by 1996, Ligand/Smithkline Beecham had identified a lead compound in its investigation of potential hematopoetic growth factors. Is this a correct reading of the chart? I guess my question is this: how do we know that the lead compound selected in 1996 is not the one (SB247464) reported in Science last week? Based on the submission date for the manuscript, it seems possible that the murine specificity may not have been discovered until late 1997 or early 1998, and this may have been the lead compound in question up until that discovery. Thus, there might not be another human-specific compound yet. Am I making myself clear? I'm not a Ligand naysayer. I just want to try to fully understand the implications of the Science articles. I am also unable to look back at past annual reports since my copies were lost in a recent flood. Thanks for your help, and best wishes. Lel

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