Bluegreen,
Not much input I could give there. I am a cardiac perfusionist, (specialist with heart-lung machines, oxygenators, artifical hearts, etc.). I work with a group of cardiac surgeons and if it were not for my cheer leading, they would have never heard of XOMA or BPI.
I talked with our consult for infectious diseases and he was also clueless, however he was very intrigued with the concept. I've seen plenty of post-op infections over the last 25 years, and if you get behind the curve and the situation deteriorates to sepsis, you're in deep trouble. The inflammatory cascade causes a rapid downward spiraling that is extremely difficult to halt. Obviously a drug like Neuprex would be a literal lifesaver. It would represent a paradigm shift in the treatment of sepsis, right now the treatment is reactive, in other words you treat the symptoms as they manifest. |
