AMGEN Message Board - Msg: 53669

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Biotech / Medical : AMGEN

AMGN 297.00

+0.2%

3:59 PM EST

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From: Frank Stein	4/14/1996 4:44:00 AM
	of 42

Having the leptin receptor will allow a company to figure out exactly what downstream events occur enabling leptin to exert its effects. This info will present several opportunities for drug intervention. Without the receptor, Amgen is limited to drug intervetion only at the level of the ligand. Without the receptor, it will be very difficult to determine how leptin works . However it is not far-fetched to think that modification of the ligand will lead to an effective drug. Yet, i am amazed that Amgen could get scooped on this. Amgen should have both the receptor and ligand ! ! What happened?

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