Lidak Pharm. [LDAKA] Message Board

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Biotech / Medical : Lidak Pharm. [LDAKA]

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To: GARY EARLS who wrote (10)	12/11/1996 1:20:00 AM
From: John Zwiener	of 1115

Hi Gary, I'm not a BI follower. I talked wiith Lisa Katz with investor relations (daughter of Dr Katz). For once I got definite info from this company (for that matter, this is the first time I got lots of info from any company) As usual, she did not know of any specific news that caused the price spike. That's what I expected. What I didn't expect was the specific answers to my other questions. To summarize: 1) Why did the phase II studies look so good and the phase III studies show equivical results? (I had considered fraud, sabotage, etc.) According to Lisa Katz (LK) , the placebo for the phase II study was made by Yamanuchi (European partner) and they made an error when mixing it up. They baked the stuff before adding some ingredient instead of visa versa. This created a different substance than was intended. This incorrect placebo was used in the Phase II studies by both Lidak and Yamanuchi. However, this incorrect placebo lacked any activity (as it was supposed to) and as a result, Lidakol showed very significant activity. The Phase III placebo was made Correctly by Lidak and as it turned out, seems to have shown it's own antiviral activity. 2) Why did you use a pla

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