Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 206.36

+1.4%

Nov 26 3:59 PM EST

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To: Machaon who wrote (23757)	7/31/1998 2:09:00 PM
From: J Stone	Read Replies (1) of 32384

Re: Targretin trails for Diabetes. I thought Henry, or one of the other biochem. types, commented a few months back that there was a potentially problematic issue with Targetin raising levels of a particular metabolic element above the healthful limit. My recollection was that Targretin may not be the Type II diabetes savior people were hoping for because of this; however, I believe Ligand has next generation compounds related to Targretin that should offer safer profiles. Of course, my recollections relating to Targretin could be quite faulty. The one thing I do know is that human renal systems are very similar to mouse renal systems, so that if Targretin effectively handled Type II diabetes well in mice there's a 99% probability it would do the same in humans barring the matter of undesired side-effects. FWIW Jeff

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