SNAP Message Board - Msg: 5466952

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Biotech / Medical : SNAP

SNAP 7.465

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3:59 PM EST

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To: Biotech Jim who wrote (30)	8/11/1998 1:02:00 PM
From: Biomaven	of 124

BJ, I heard that there are some cardiovascular side effects of this drug and I wonder if they are mechanism related. If so, then there will be no big splash with this mechanism. All I know is what was reported in the filing: To date, in the limited Phase II clinical studies, LY334370 was observed to reduce or eliminate migraine pain. According to Lilly, no cardiovascular side effects have been observed, although at certain higher doses side effects such as asthenia, dizziness and/or somnolence were observed. -------- If there really are _no_ cardiovascular or other serious side-effects and it works as well as the other triptans, then eventually we could be looking at an OTC drug, which would be a very big splash indeed. Peter

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