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Biotech / Medical : Agouron Pharmaceuticals (AGPH)

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To: Joe E. who wrote (5134)8/13/1998 12:10:00 PM
From: John Metcalf  Read Replies (1) of 6136
 
Excuse me for jumping in, Joe. In general, physicians advise HIV positive women not to become pregnant, because HIV is almost always transmitted to the child. Unprotected sex is also not advised. Protease inhibitors would not routinely be withheld to women of childbearing age, because they are advised to be cautious in procreation and against becoming pregnant. For those women who are pregnant and HIV-positive, there are studies showing that AZT is of some value in preventing transmission to the child.

In regard to the recent press for Thalidomide, Celgene has approval for use in leprosy. Like HIV, leprosy is a serious condition in which reproduction is not recommended.

Canada was not withholding the benefits of nelfinivir from people who needed it. Agouron has had an expanded access program in Canada in which 1,200 adults were receiving the drug (paid by AGPH). There has also been an expanded access program for children. AGPH's news release on Canadian approval did not mention the number of children in the program.
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