James:
I would suggest a cruise of the recent 10-Q and 10-K. This will give you a concept of the quality of the research capacities behind the new Vanderbilt/diabetes agreement, for which a corporate partner is being sought (search term is Granner DK)....
Yamada K, et al. [See Related Articles]
Efficient large-scale transformation of yeast.
Biotechniques. 1998 Apr; 24(4): 596-598. No abstract available.
PMID: 9564532; UI: 98225719.
Scott DK, et al. [See Related Articles]
Further characterization of the glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene. The role of
the glucocorticoid receptor-binding sites.
Mol Endocrinol. 1998 Apr; 12(4): 482-491.
PMID: 9544984; UI: 98204545.
Sutherland C, et al. [See Related Articles]
Activation of the ras mitogen-activated protein kinase-ribosomal protein kinase pathway is not required for the
repression of phosphoenolpyruvate carboxykinase gene transcription by insulin.
J Biol Chem. 1998 Feb 6; 273(6): 3198-3204.
PMID: 9452431; UI: 98123082.
Koval JA, et al. [See Related Articles]
Regulation of hexokinase II activity and expression in human muscle by moderate exercise.
Am J Physiol. 1998 Feb; 274(2 Pt 1): E304-E308.
PMID: 9486162; UI: 98147116.
O'Doherty RM, et al. [See Related Articles]
Analysis of insulin-stimulated skeletal muscle glucose uptake in conscious rat using isotopic glucose analogs.
Am J Physiol. 1998 Feb; 274(2 Pt 1): E287-E296.
PMID: 9486160; UI: 98147114.
Printz RL, et al. [See Related Articles]
Hexokinase II gene: structure, regulation and promoter organization.
Biochem Soc Trans. 1997 Feb; 25(1): 107-112. Review. No abstract available.
PMID: 9056853; UI: 97209678.
Sutherland C, et al. [See Related Articles]
Oxidative and chemical stress mimic insulin by selectively inhibiting the expression of phosphoenolpyruvate
carboxykinase in hepatoma cells.
Diabetes. 1997 Jan; 46(1): 17-22.
PMID: 8971075; UI: 97126151.
Scott DK, et al. [See Related Articles]
The orphan receptor COUP-TF binds to a third glucocorticoid accessory factor element within the
phosphoenolpyruvate carboxykinase gene promoter.
J Biol Chem. 1996 Dec 13; 271(50): 31909-31914.
PMID: 8943235; UI: 97112982.
O'Brien RM, et al. [See Related Articles]
Regulation of gene expression by insulin.
Physiol Rev. 1996 Oct; 76(4): 1109-1161. Review.
PMID: 8874496; UI: 97028483.
O'Doherty RM, et al. [See Related Articles]
Transcription of the rat skeletal muscle hexokinase II gene is increased by acute exercise.
J Appl Physiol. 1996 Aug; 81(2): 789-793.
PMID: 8872647; UI: 97026469.
Osawa H, et al. [See Related Articles]
Identification and characterization of basal and cyclic AMP response elements in the promoter of the rat hexokinase II
gene.
J Biol Chem. 1996 Jul 19; 271(29): 17296-17303.
PMID: 8663388; UI: 96291882.
Osawa H, et al. [See Related Articles]
Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin.
J Biol Chem. 1996 Jul 12; 271(28): 16690-16694.
PMID: 8663315; UI: 96279242.
Wang JC, et al. [See Related Articles]
Hepatic nuclear factor 3 is an accessory factor required for the stimulation of phosphoenolpyruvate carboxykinase gene
transcription by glucocorticoids.
Mol Endocrinol. 1996 Jul; 10(7): 794-800.
PMID: 8813720; UI: 96408713.
Chang PY, et al. [See Related Articles]
Overexpression of hexokinase II in transgenic mice. Evidence that increased phosphorylation augments muscle glucose
uptake.
J Biol Chem. 1996 Jun 21; 271(25): 14834-14839.
PMID: 8662926; UI: 96278971.
Ardehali H, et al. [See Related Articles]
A novel (TA)n polymorphism in the hexokinase II gene: application to noninsulin-dependent diabetes mellitus in the Pima
Indians.
Hum Genet. 1996 Apr; 97(4): 482-485.
PMID: 8834247; UI: 96431165.
Scott DK, et al. [See Related Articles]
Identification and charaterization of the second retinoic acid response element in the phosphoenolpyruvate carboxykinase
gene promoter.
J Biol Chem. 1996 Mar 15; 271(11): 6260-6264.
PMID: 8626419; UI: 96198086.
Taylor RW, et al. [See Related Articles]
Variant sequences of the Hexokinase II gene in familial NIDDM.
Diabetologia. 1996 Mar; 39(3): 322-328.
PMID: 8721778; UI: 96361932.
Sutherland C, et al. [See Related Articles]
New connections in the regulation of PEPCK gene expression by insulin.
Philos Trans R Soc Lond B Biol Sci. 1996 Feb 29; 351(1336): 191-199. Review.
PMID: 8650266; UI: 96244093.
Parsa R, et al. [See Related Articles]
Induction of the glucokinase gene by insulin in cultured neonatal rat hepatocytes. Relationship with DNase-I
hypersensitive sites and functional analysis of a putative insulin-response element.
Eur J Biochem. 1996 Feb 15; 236(1): 214-221.
PMID: 8617267; UI: 96184900.
Ludwig DS, et al. [See Related Articles]
Examination of the phosphoenolpyruvate carboxykinase gene promoter in patients with noninsulin-dependent diabetes
mellitus.
J Clin Endocrinol Metab. 1996 Feb; 81(2): 503-506.
PMID: 8636258; UI: 96225510.
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