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Biotech / Medical : Cel-Sci Corp (AMEX:CVM) (was HIV)
CVM 6.660+0.5%Nov 14 9:30 AM EST

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To: Tom Shutters who wrote (2194)10/27/1998 4:04:00 PM
From: Tom Shutters  Read Replies (1) of 2836
 
"Expert Dispels AIDS Vaccine Myths"

..."Vaccines must prevent all disease. "Few vaccines prevent infection completely," said Clements-Mann. "Far from providing sterilizing immunity -- that is, the complete prevention of infection -- the goal for all vaccines of public health importance is to provide sufficient immunity to ameliorate disease."...

..."Multiple field trials are the rule for successful vaccine development, not the exception. Rather than focus on the idea of a single, ultimate trial, the expectation must be that multiple trials will be required, with each successive field trial being designed to address questions raised by the positive or negative findings in earlier trials."...

"...If a vaccine trial fails to demonstrate efficacy, the development of effective vaccines is set back. "On the contrary," said Clements-Mann, "by finding out why a vaccine failed in efficacy trials, scientists and manufacturers can then modify it, and in subsequent trials demonstrate its ability to provide substantial protection to target populations."...

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