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Biotech / Medical : IDPH--Positive preliminary results for pivotal trial of ID

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To: Webhead who wrote (1609)10/29/1998 8:32:00 PM
From: A.J. Mullen  Read Replies (1) of 1762
 
Webhead, I see you know something of which you speak. Please bear with me. I have only half-knowledge of facts and guesses, and the biggest problem is that I am not sure which is which.

I can see now the logic of mopping up circulating lymphocytes before labelling. I am still troubled by Maurices' idea that Rituxan will harden the CD20. You say most cell-surface proteins turn over rapidly once labelled, but isn't that the idea of Rituxan. If Rituxan hasn't worked, is that not because some cd20-Rituxan conjugates are stable?
The press-release mentioned YT-rituxan treatment being administered over eight days.
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