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Biotech / Medical : IDPH--Positive preliminary results for pivotal trial of ID
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To: DMB who wrote (1475)11/13/1998 4:57:00 AM
From: Maurice Winn1 Recommendation  Read Replies (1) of 1762
 
bloodjournal.org

This says "An analysis of prognostic factors showed that response rates were lower in patients with refractory disease, patients with lymphoma not classified as DLCL and patients with a tumor larger than 5cm in diameter. DLCL and MCL patients had response rates of 37% and 33% respectively."

That tells me that Rituxan caused killing of billions of lymphoma cells without undue risk to the patient.

Therefore it seems that my treatment of:

Surgical excision, 3 x CHOP plus Rituxan, followed by Oncolym then cod liver oil, vitamin C, E and a good sleep is better than 3 cycles of CHOP and radiotherapy for a stage I diffuse large cell lymphoma.

The 37% response rate they mention means that there are an awful lot of distant metastases which will be killed. Since there are no bulky tumors in the Stage I excised patients, they are going to get much better cure rates.

Is that how you read those results?

Since Stage 1A 2cm excised tumor, IPI0, Intermediate Grade, Diffuse, Large B-cell, Non-Hodgkin lymphoma patients age 21 have cure rates of 80%, it seems that by the addition of Rituxan to the usual therapy, this cure rate could be increased to around 90% or more. Not bad for not much cost and not much health risk.

Thanks for any comments you might have,

Maurice

PS: Here is a bit of basis for cod liver oil maybe being useful in lymphoma though this article is talking leukemia. Vitamin D is also unpleasant for melanoma cells.
bloodjournal.org
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