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Biotech / Medical : Ligand (LGND) Breakout!
LGND 197.62+0.1%Dec 24 12:59 PM EST

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To: Alper H.YUKSEL who wrote (26557)11/17/1998 4:19:00 AM
From: Cheryl Galt  Read Replies (1) of 32384
 
Alper and all, I can't guess the price of Panretin get, but I did price Allergan's new Tazorac gel - approved June 1997.

TAZORAC (a receptor-selective retinoid) seems to be a current preferred topical treatment for mild/moderate psoriasis and severe acne.

Tazorac (tazarotene) is not cheap.
It comes in 0.05% and 0.1%.
Bartell didn't carry the 0.05% gel.

For the 0.1% gel
30g tube -- $079.79
100g tube - $246.29
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To limit side effects, the stuff must be put on carefully
-- sparingly, and ONLY on the lesions.

I assume Panretin gel would need the same precautions, spelled out in this NPF article:

March 1998 - Tazorac Needs Attention to Detail
Misuse or misunderstanding may lead to early termination of therapy
psoriasis.org

Reading the above article, I should think that if during trials patients apply the gel at home, their expertise -- or lack of it -- could greatly impact the test results.
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General info from the National Psoriasis Foundation Website:
psoriasis.org
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BTW, for pregnant or nursing women, tazorac is Category X
-- totally counter-indicated, because it can cause severe birth defects.

Any informed speculation regarding how Panretin gel might compare to Tazorac,
for psoriasis and acne?

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Now I'd better hit the sack, if I'm to be up in time for a possible bargain basement special east coast time.

Alper, what time is it in Turkey?
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