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Biotech / Medical : Sepracor-Looks very promising

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To: Vector1 who wrote (1435)11/17/1998 9:06:00 AM
From: Biomaven  Read Replies (1) of 10280
 
V1,

My take on this early data is that it is comparable to Detrol and better than straight oxy, but not as good as the numbers claimed by Alza for their time-release version. I view it as a viable drug, with the distinct possibility that a time-release version would be better than the Alza drug.

From what I heard, SEPR has been beating the drums for ages saying that they didn't know if it was going to show efficacy at all. I certainly didn't hear that "the company had been encouraging
enthusiasm in advance of the release."

(S)-oxy is quite different from all their other single isomer drugs, in that the two isomers have different modes of action, not just different side effects. Thus Maris's attempt to say that the data "shows the risks of single isomer development" means that he either doesn't understand this, or he does understand it and he's just mad at the company. In general he seems more concerned with Alza than SEPR.

Peter
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