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Biotech / Medical : Centocor ( CNTO )
CNTO 0.000010000.0%Jan 29 9:30 AM EST
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To: Steve Fujikawa who wrote (848)11/24/1998 9:35:00 AM
From: Henry Niman  Read Replies (1) of 965
 
I think that the earlier versions elicited a more powerful immune reaction, which led to problems when the patients were retreated several years later with the newer batch. However, at this point, I believe that the explanation has considerable speculation built into it, and it's not clear that new batches will not elicit similar reactions when the patient is challenged at a later date.
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