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Biotech / Medical : Biotransplant(BTRN)
BTRN 27.84+0.4%Jan 9 4:00 PM EST
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To: scaram(o)uche who wrote (178)12/10/1998 10:23:00 AM
From: scaram(o)uche  Read Replies (1) of 1475
 
The BTRN presentation, about four hours from now.......

2:40
Direct Approaches for the Induction of Transplantation Tolerance for Xenotransplantation
Julia L. Greenstein, Ph.D.
Success in the use of human organ transplantation has led to a critical shortage of organs. Use of
animal organs offers the hope of addressing this need. Tolerance induction may be essential for
successful clinical use of animal organs. Tolerance to xenogeneic cells or solid organs can be induced
by using multiple approaches. Specific tolerance can be induced by establishing swine-into-primate
bone marrow chimerism, by gene therapy utilizing SLA-DR containing retroviral vector transduction of
autologous bone marrow and in a murine model by swine thymus transplantation.
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