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Biotech / Medical : ARIAD Pharmaceuticals
ARIA 23.990.0%Feb 17 4:00 PM EST

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To: scaram(o)uche who wrote (9)1/27/1997 3:00:00 PM
From: Boyce Burge   of 4474
 
Great post. Very insightful.

I talked to a couple of Stanford molecular biologists yesterday who feel that the gene therapy area may become broken into segments: some companies providing specific vectors (VICL, TGEN), others providing ex vivo expertise (CEGE?) and still others providing fine tuning of gene expression (presumably ARIA). Cross licensing may become widespread. I also heard that the ARIA approach of grafting immunophilin-like regions onto the proteins of interest does not work for all genes...you just have to try it and cross your fingers.

Crabtree is said to be looking for a "spherical" small molecule dimer that can join the 2 halves of the relevent proteins in the most natural way. With his probable eventual success, the value of the ARIA piece of the puzzle will increase greatly.

I think the warrants are a good buy here (at 1 13/16) especially with the OpCo recommendation.
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