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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ)

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To: VLAD who wrote (17735)	1/13/1999 4:16:00 PM
From: RT	Read Replies (3) of 23519

Notes Some suggestions on what to look for: -New Rxs: The key to the health of a new product. Look for volume, market share and growth trends. Viagra New Rxs are expected to plateau and decline due to heavy initial trial usage. Holidays and major specialty conventions (such as the AUA Meeting) will effect weekly totals. -Refill Rxs: An important indicator of the efficacy and toleration of a new product particularly one for prn therapy such as ED. These patients will not refill a product that is not working or is causing adverse reactions. -Refill/New Rx Ratio: Another indicator of a product's success. After an initial launch period of 4-6 months, a successful new product should have a refill ratio of at least 50%. Conversely, a product with a refill ratio of less than 50% after 4-6 months may not have been viewed as effective, well-tolerated, or available. In addition, a ratio of greater than 110% may result from a sharp decline in new specification due to alternative new therapies ....while the remaining satisfied patients continue to refill their Rxs. If this ratio is significantly higher than historical norms, the product may be in trouble.

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