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Biotech / Medical : Paracelsian Inc (PRLN)
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To: Jonathan Schonsheck who wrote (4082)1/15/1999 10:25:00 AM
From: Jonathan Schonsheck  Read Replies (1) of 4342
 
Product Discovery and Development

(2) Product Discovery and Development. The Company owns an extract
library of approximately 2,764 Traditional Chinese Medicines and other plant
materials which it has screened using its proprietary screening technology.
Through this screening process, the Company has identified ten (10) potential
therapeutic compounds that the Company intends to target as drug candidates.
5<PAGE>
In July 1998, the Company entered into a collaborative research agreement with
the Southern Research Institute ("SRI") in Birmingham, Alabama. Under the
Agreement, the scientists from the two companies will work to identify and
develop compounds, such as Andrographalide, from the Company's TCM extract
library, which have the potential to become anti-cancer pharmaceuticals. Several
of the most promising extracts and Andrographalide are the subjects of animal
trials currently underway at SRI. Management expects to obtain the results of
the animal tests in the Spring of 1999. If the results are positive, SRI and the
Company intend to proceed with the next phase of clinical trials. The goal of
the SRI/Paracelsian collaboration is to partner with a major pharmaceutical
partner to develop any potential drug candidates in the shortest possible time
period.
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