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Microcap & Penny Stocks : Cryogenic Solutions Inc. (CYGS)

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To: Graham Marshman who wrote (3517)1/19/1999 6:19:00 PM
From: Hogger  Read Replies (1) of 4028
 
Graham,

Probably Dr. Graystoned would not understand what it says, and certainly not what it means ... however, for the more learned, here is the text of the release and the link:

go2net.newsalert.com

Intracellular Synthesis of Telomeric Repeat Appears Lethal To Malignant Cells

Business Wire - January 19, 1999 15:19

HOUSTON--(BUSINESS WIRE)--Jan. 19, 1999--Cryogenic Solutions Inc. (OTC BB:CYGS)announced the positive results of its experimental expression of the (TTAGGG)n oligonucleotide sequence in HeLa cells. As expected, intracellular expression of the (TTAGGG)n oligo appeared to select against malignant cells which expressed the telomeric repeat whereas HeLa cultures transfected to express a control sequence of the same length continue to thrive.

The company's ssDNA expression vector uses viral encoded genes to produce intracellular oligonucleotide sequences of any desired composition, which effectively avoids some of the major hurdles associated with antisense delivery.

The vector can be described as a custom designed biological factory that synthesizes single-stranded DNA inside living cells. The researchers are able to program the sequences of ssDNA to be manufactured once the vector has entered a cell.

It is anticipated that the ssDNA expression vector will soon allow biomedical research to graduate from cell cultures to live animal studies, especially those involving antisense technologies and therapies.

The (TTAGGG)n sequence is one of many that have been shown in vitro to kill cancer cells. A series of subsequent in vivo studies are planned to demonstrate that the patented product performs as expected with a variety of catalogued sequences.

CONTACT: Cryogenic Solutions Inc., Houston
Dell Gibson, 713/780-1399

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