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Biotech / Medical : XOMA. Bull or Bear?
XOMA 26.06+0.3%Dec 26 9:30 AM EST

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To: aknahow who wrote (8428)1/22/1999 4:39:00 PM
From: Biomaven  Read Replies (1) of 17367
 
george,

A perfect example of the dangers of subset analysis. From a description of ABTI's previous study:

In the upper GI surgery stratum (non-colorectal, n=391), there was a prominent and statistically significant reduction in serious post-operative infections in both Betafectin dose groups versus placebo. The percentage of patients with serious infections decreased 39% in the two treated groups compared to placebo; 46 of 129 (36%) patients in the placebo group experienced serious infection, while 29 of 132 (22%) patients in the 0.5 mg/kg Betafectin group and 28 of 130 (22%) patients in the 1.0 mg/kg Betafectin group experienced serious infection (p=0.01). This key result provided the basis for the ongoing confirmatory trial in upper GI surgery patients.

Peter
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