The problem with the study on Androvir and AZT is that it was in vitro not in vivo, and I think that remains the case. An in vivo study remains to be done, although information may be forth coming when Androvir goes to market. I think many of the current cocktails contain AZT and a protease inhibitor, and various other medications--I don't think there is one standard cocktail. When Androvir goes to market, since it is safe, many current users of various cocktails will probably add Androvir on their own and hopefully much good and usefull data will come from that.
I believe severe nausea is one of the side effects which often results from AZT. Some AIDS groups and researchers, however, are convinced that AZT itself is so toxic that in many instances it does more to hasten deterioration and death then to slow them down. It probably is the case that in some it is helpful and others harmful, for idiosyncratic reasons, as with chemotherapy for leukemia or lymphoma where the hope is to kill the cancer before killing the patient. Hopefully, Androvir or cocktails involving Androvir can tip the scales further in the direction of therapeutic results with much reduced side effects. Again however, as far as I know, Androvir has not yet been tested with AZT in vivo.
Larry |
